Epicutis Lipid Serum is the cornerstone of the Epicutis system — a minimalist eight-ingredient barrier repair and anti-inflammatory serum built around TSC (Disodium Tetramethylhexadecenyl Succinoyl Cysteine), a patented bioactive lipid molecule developed at Princeton University that addresses inflammation, barrier repair, and UV protection simultaneously from within the skin's lipid barrier structure. Physician-developed for sensitive, post-procedure, and barrier-compromised skin.

TSC is a synthetic lipid that mimics the skin's natural ceramide-like barrier building blocks — it inserts into the stratum corneum lipid bilayer to reduce inflammation at the cellular level, blocks UVA/UVB-induced free radical generation within the barrier, provides antioxidant protection against environmental damage, and helps prevent the collagen breakdown triggered by UV-induced inflammation. Unlike topical anti-inflammatories that simply suppress surface redness, TSC works within the lipid matrix where inflammation originates. Sodium Hyaluronate (Hyaluronic Acid) provides deep hydration and plumping. Glycerin and Propanediol provide additional humectant hydration and texture optimization. Only 8 total ingredients — no fragrances, preservatives, or fillers. Epicutis is a Princeton University-rooted clinical skincare brand founded by dermatologist Dr. Steven Rosen, M.D., built around patented lipid bioactive technology (TSC — Disodium Tetramethylhexadecenyl Succinoyl Cysteine) developed at Princeton University. Each formula is designed around a minimal, clean ingredient philosophy — only ingredients that serve a clear functional role. Available at Beauty Riche — authorized Epicutis retailer with same-day shipping.

Epicutis Lipid Serum 1oz 30ml – TSC Barrier Repair Anti-Inflammatory Serum