Alastin Renewal Retinol 0.5 is a physician-developed, award-winning retinol serum that delivers clinical anti-aging results with significantly better skin tolerance than standard retinol formulas — achieved through lipid encapsulation technology that improves retinol delivery, potency, and stability while dramatically reducing the redness, peeling, and irritation that cause most patients to abandon retinol therapy. Winner of InStyle Best Beauty Buys 'Best Wrinkle Treatment 2021'.

Retinol encapsulated in a solid lipid nanoparticle — this delivery system protects the retinol molecule from air oxidation, maintains stability and potency from bottle to skin, and provides a controlled, gradual release of retinol into the dermis that improves penetration depth while reducing surface irritation. The lipid carrier itself supports the skin's natural collagen production pathway, adding a secondary anti-aging benefit beyond retinol alone. Silver Mushroom (Tremella Fuciformis) provides intense hydration significantly beyond standard hyaluronic acid — making this one of the most hydrating retinol formulas available, reducing the dehydration common with retinol use. Oat Kernel Extract delivers calming, anti-irritant activity. Hydroxymethoxyphenyl Decanone supports natural hyaluronic acid levels. CoQ10 (Ubiquinone) protects the retinol molecule from oxidative degradation during storage and use.

Apply 1 pump to face in the evening only. Begin 2–3 evenings per week, increasing gradually to nightly as tolerated. Use daily SPF 30+. Not for use during pregnancy. Available at Beauty Riche — authorized Alastin retailer with same-day shipping.

Alastin Renewal Retinol 0.5 Face Serum 1oz – Lipid-Encapsulated Retinol for Texture & Tone